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what’s IMBRUVICA® (ibrutinib)?
IMBRUVICA® (ibrutinib) is a prescription remedy used to deal with adults with:
Mantle cell lymphoma (MCL) who’ve acquired at least one prior treatment
persistent lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL)
chronic lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL) with 17p deletion
Waldenström’s macroglobulinemia (WM)
Marginal area lymphoma (MZL) who require a remedy over-the-counter aid of mouth or injection (systemic remedyover the counter) and have acquired a positive kind of earlier treatment
continual graft as opposed to host sickness (cGVHD) after failure of one or greater strains of systemic over the counter
It isn’t always known if IMBRUVICA® is secure and powerful in children.
DOSAGE AND management
1.MCL and MZL: 560 mg taken orally as soon as each day (four a hundred and forty mg tablets once each day)
2.CLL/SLL, WM, and cGVHD: 420 mg taken orally as soon as each day (3 a hundred and forty mg capsules as soon as every day).
tablets must be taken orally with a tumbler of water. Do now not open, wreck, or chunk over the counter pills
essential aspect effect records
before taking IMBRUVICA®, tell your healthcare provider about all your clinical conditions, which include in case you:
have had recent surgical operation or plan to have surgical operation. Your healthcare issuer might also forestall IMBRUVICA® for any deliberate scientific, surgical, or dental technique
have bleeding issues
have or had heart rhythm troubles, smoke, or have a medical situation that will increase your danger of heart ailment, including high blood pressure, high cholesterol, or diabetes
have an contamination
have liver problems
are pregnant or plan to come to be pregnant. IMBRUVICA® can harm your unborn child. if you are capable of grow to be pregnant, your healthcare issuer will do a being pregnant take a look at earlier than starting remedy with IMBRUVICA®
ladies should no longer become pregnant at some stage inover the counter remedy and for 1 month after over the counter remaining dose of IMBRUVICA®
males ought to avoid getting lady partners pregnant for overover the counter remedy and for 1 month after over the counter last dose of IMBRUVICA®
are breastfeeding or plan to breastfeed. You and your healthcare issuer ought to determine if you’ll take IMBRUVICA® or breastfeed
inform your healthcare issuer about over-the-counter medicines you are taking, togeoverover the counter prescription and drug treatments, nutrients, and herbal supplements. Taking IMBRUVICA® with certain different medicines may have an effect on how IMBRUVICA® works and may purpose facet results.
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